Arsenal will face Porto in the last 16 of the 2023-24 Champions League, while Real Madrid tackle RB Leipzig in the first knockout round.
Elsewhere, European title holders Manchester City are due to lock horns with FC Copenhagen and Barcelona must overcome Napoli in order to reach the quarter-finals.
There are also heavyweight ties involving Harry Kane’s Bayern Munich, who come up against Lazio, and Paris Saint-Germain going head-to-head with Real Sociedad.
There will be plenty of U.S. interest in the tie involving PSV and Borussia Dortmund – with the likes of Ricardo Pepi, Sergino Dest and Gio Reyna hoping to figure prominently in that contest.
Inter made it all the way to the final last season, before coming unstuck against Pep Guardiola’s Treble-winning City machine, and they are unlikely to have things all their own way against La Liga heavyweights Atletico Madrid.
CHAMPIONS LEAGUE LAST 16 DRAW IN FULL
Porto vs Arsenal
Napoli vs Barcelona
Paris Saint-Germain vs Real Sociedad
Inter vs Atletico Madrid
PSV vs Borussia Dortmund
Lazio vs Bayern Munich
FC Copenhagen vs Manchester City
RB Leipzig vs Real Madrid